Your main task is to provide toxicology and pathology expertise and mechanistic understanding in the interpretation of nonclinical findings, and their relevance to humans. Histopathological evaluation and peer review of regulatory and exploratory toxicological and efficacy studies, including interpretation of clinical pathology results, is also essential part of your job. You serve also as a nonclinical safety expert in multifunctional project teams on discovery and development projects and build up the holistic safety knowledge of the molecule from the beginning to the end of projects. You design and oversee execution of nonclinical toxicology studies and programs for small and large molecules during discovery and development phase.
Description of unit
Orion is a globally operating Finnish pharmaceutical company - a builder of well-being. Orion develops, manufactures and markets human and veterinary pharmaceuticals, active pharmaceutical ingredients and diagnostic tests. The company is continuously developing new drugs and treatment methods. The core therapy areas of Orion's pharmaceutical R&D are central nervous system (CNS) disorders, oncology and respiratory for which Orion develops inhaled Easyhaler® pulmonary drugs. Orion's net sales in 2017 amounted to EUR 1,085 million and the company had about 3,500 employees. Orion's A and B shares are listed on Nasdaq Helsinki.
Translational Safety organization is part of Global Translational Pharmacology & Safety Sciences at Orion R&D. The organization is responsible for the preclinical safety assessment of new drug candidates during various stages of the drug discovery and development process. The function designs and executes safety pharmacology and toxicology studies performed either in our own facilities (exploratory safety studies in discovery phase) or in contract research organizations (GLP studies in development phase). Translational Safety organization supports research and development projects in all Orion's core therapy areas.
- DVM/MD and/or PhD in veterinary medicine, human medicine, biology or natural sciences
- Engaged personality with enthusiasm in veterinary and toxicological pathology, certification in pathology is desirable
- Expertise in experimental and toxicological pathology is essential
- Expertise in clinical pathology and immunology
- Experience in histological methods and digital pathology
- Working experience in safety assessment in discovery & development in pharma industry is desirable
- Understanding of drug development of small and large molecules and comparative safety assessment (animal species vs human) is desirable
- Excellent networking (internal, external) capabilities
- Fluent in English
We offer exciting opportunities to create and have an impact to the future therapies for patients.
We also offer you attractive career development opportunities for using your own strengths for development, highly interesting R&D pipeline and enthusiastic working environment. Appreciation of personnel and constant development are part of our core values. The culture of Orion R&D is informal and we enjoy working together.
We are passionate about the patient welfare and are The Voice of Science and the Patient – do you share the same values?
The location is Turku (preferred)/ Espoo (optional), Finland. If moving to Finland, please check the areas where Finland is considered a leader in the world by copying this link to your web browser http://www.huffingtonpost.com/ira-kalb/finland-is-still-the-worl_b_10774930.html